GCCCF secretary general Abdulrahim Naqui sealed the deal with US chamber’s external relations deputy chief Dan Chrisman.
The contract aims at providing support for GCC small and medium businesses and to benefit from the US expertise.
Forums, conferences, workshops and training courses will also be held jointly, including an annual GCC-US symposium.
Crude oil and oil-based products represent the major bulk of GCC exports to the US.
Meanwhile, the GCC countries import machinery and other technological equipment.
The US attracts more than half of GCC investments abroad, estimated at around $ 1.4 trillion.
The GCCCF has already signed a similar memorandum of understanding with the EU Chambers Union to boost bilateral exchanges, enhance the volume of investments, promote services and secure transfer of technology.
Providing crucial support to promote small and medium businesses in the GCC zone was also part of the deal.
Similar deals were also sealed with Arab German Chambers, Gulf Industrial Consultancy Organisation, UNIDO, Arab British Chamber, Asian Chambers Union and other regional and international enterprises.